University of Louisville to Operate Kentucky’s New Defense Innovation Hub

Collaboration in the Defense Innovation Hub at the University of Louisville

Louisville, KY, November 25, 2025

The U.S. Department of War has chosen the University of Louisville to manage Kentucky’s new Defense Innovation OnRamp Hub. This initiative aims to enhance local contributions to national defense technology by fostering collaboration between local talent and defense needs, while empowering small businesses and entrepreneurs in the region.

University of Louisville to Operate Kentucky’s New Defense Innovation Hub

A Key Step Towards Enhancing Kentucky’s Defense Technology Sector

LOUISVILLE, Ky. — The U.S. Department of War has selected the University of Louisville (UofL) to operate Kentucky’s new Defense Innovation OnRamp Hub, aiming to enhance the state’s contributions to national defense technology. This initiative promises to connect local talent and technology companies directly with the needs of the defense sector, igniting collaboration that may stimulate further economic growth in the region.

By leveraging UofL’s existing research capabilities and its focus on innovation, this new hub is poised to empower local entrepreneurs and small businesses. In a time where reducing barriers to entry can often yield significant advancements for the economy, the OnRamp Hub represents a vital opportunity for Kentucky’s workforce to engage meaningfully with national defense initiatives while promoting regional entrepreneurial spirit.

Hub’s Mission and Location

The Defense Innovation Unit (DIU), a branch within the U.S. Department of War, has chosen UofL to manage this new hub, which will be established in the Nucleus Building at 300 East Market Street on the J.D. Nichols Campus for Innovation and Entrepreneurship. The hub aims to facilitate synergy among academics, startups, and seasoned defense companies, nurturing an environment where innovative solutions can flourish. Under the direction of William Fortune, a Kentucky-native with experience in both military and civilian leadership, the hub aims to provide a range of services designed to accelerate innovation and strengthen the defense industry in Kentucky.

UofL’s Role and Capabilities

The J.B. Speed School of Engineering at UofL will play an integral role in the mission of the hub. With established strengths in manufacturing, robotics, cybersecurity, and micro and nano technology, UofL can offer rich resources to enhance regional capabilities in these critical areas. The university’s existing partnerships with local defense and manufacturing entities position it well to support both small businesses and established industries, fostering a collaborative atmosphere that advances Kentucky’s economic landscape.

Significance and Support

Prominent local leaders have expressed immense support for UofL’s new role. With the establishment of the Defense Innovation Unit OnRamp Hub in Kentucky, opportunities for defense companies and local innovators to contribute directly to national security will expand. Such initiatives not only reinforce UofL’s commitment to advancing defense technology but also serve to uplift the manufacturing sector throughout Kentucky, allowing small businesses to thrive alongside large defense contractors.

Background on DIU OnRamp Hubs

The Defense Innovation OnRamp Hubs represent a broader strategy by the DIU to cultivate innovative solutions in defense technology by lowering entry barriers for talent and resources in various sectors, including academia and startups. Kentucky’s inclusion in this initiative echoes a national trend as other states have also embraced the creation of OnRamp Hubs. Through this structured approach, Kentucky’s unique pool of talent and technological innovations will have unprecedented opportunities to collaborate with the Department of War, further strengthening its national defense efforts.

Related Initiatives

UofL has previously collaborated with the Department of Defense on numerous initiatives, further establishing its reputation as a valuable asset in national security. Recently, UofL was selected to be part of two new academic networks aimed at enhancing country-wide cyber defenses. This selection underscores the university’s significance in defense-related education and innovation, paving the path for future collaborations that will bolster both the local economy and national security strategies.

Conclusion

The establishment of the Defense Innovation Hub at the University of Louisville marks an exciting development for Kentucky’s economy and its small-business sector. By fostering collaboration between defense needs and local innovation, this initiative has the potential to unlock new opportunities for entrepreneurs and researchers alike. As the state continues to evolve into a crucial player in national defense technology, community support and engagement with local businesses will be more important than ever. Embracing the entrepreneurial spirit in Kentucky will ensure that the region remains at the forefront of innovation and economic growth.

FAQ

What is the purpose of Kentucky’s new Defense Innovation Hub?

The hub aims to enhance Kentucky’s contributions to national defense technology by connecting local talent and technology companies with the Department of War’s needs.

Where will the Defense Innovation Hub be located?

The hub will be located in the Nucleus Building at 300 East Market Street on UofL’s J.D. Nichols Campus for Innovation and Entrepreneurship.

Who will lead the Kentucky Defense Innovation Hub?

William Fortune, a Kentucky native with over two decades of military and civilian leadership experience, has been appointed as the director of the hub.

What areas of expertise does UofL bring to the hub?

UofL’s J.B. Speed School of Engineering will contribute expertise in manufacturing, robotics, cybersecurity, and micro and nano technology.

Key Features of Kentucky’s Defense Innovation Hub

Feature Description
Location Nucleus Building at 300 East Market Street on UofL’s J.D. Nichols Campus for Innovation and Entrepreneurship
Director William Fortune, with over 20 years of military and civilian leadership experience
Focus Areas Manufacturing, robotics, cybersecurity, micro and nano technology
Objectives Enhance collaboration between local businesses and defense needs, accelerate innovation and economic growth

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